期刊
LIFE SCIENCES
卷 97, 期 1, 页码 20-26出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.lfs.2013.10.029
关键词
Dopamine; Serotonin; Transporters; Amphetamine; Methamphamine; Cocaine; Methcathinone; Mephedrone; MDPV; Methylone; Synthetic cathinones; Bath salts; Intracranial selfstimulation (ICSS)
资金
- NIH NIDA [5R01DA033930]
This mini-review summarizes the history of cathinone and its synthesized derivatives from early records to the present day, including the appearance of synthetic cathinones in the drug combination known as bath salts. Bath salts may consist of one compound (MDPV) or combinations of MDPV and one or more other synthetic cathinones, which may also appear alone without MDPV. We briefly review recent in vitro studies of bath salts components alone or in combination, focusing on pharmacological and biophysical studies. Finally we summarize new data from in vivo procedures that characterize the abuse-related neurochemical and behavioral effects of synthetic cathinones in rats. (C) 2013 Elsevier Inc. All rights reserved.
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