期刊
LIFE SCIENCES
卷 87, 期 23-26, 页码 659-666出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.lfs.2010.10.003
关键词
PP2A; Regulatory subunit; B '; B56; PR61; Signaling pathways; Development; Tumorigenesis
资金
- NIGMS [1R01GM093217-01A1]
- NIA [1R01AG031833]
Members of the B'/B56/PR61 family regulatory subunits of PP2A determine the subcellular localization, substrate specificity, and catalytic activity of PP2A in a wide range of biological processes. Here, we summarize the structure and intracellular localization of B56-containing PP2As and review functions of B56-containing PP2As in several major developmental/cancer signaling pathways. (C) 2010 Elsevier Inc. All rights reserved.
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