期刊
LEUKEMIA RESEARCH
卷 37, 期 2, 页码 201-203出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.leukres.2012.11.007
关键词
Myelodysplastic syndromes; T-cells; T-cell receptor repertoire; Regulatory T cells
Although a burden of clinical and experimental data suggest the involvement of T-lymphocytes in the pathogenesis of myelodysplastic syndromes (MDS), the actual weight exerted by T-cells in this scenario is yet to be conclusively dissected. This brief review will try to further address this point, by running through the most relevant studies exploring the T-cell repertoire of MDS patients as well as the potential role of specific T-cell subsets such as regulatory T-cells and Th17 T-cells. (C) 2012 Elsevier Ltd. All rights reserved.
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