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注意：仅列出部分参考文献，下载原文获取全部文献信息。Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling
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Immunophenotypic features of acute myeloid leukaemia patients exhibiting high FLT3 expression not associated with mutations
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Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer
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Control of the reversibility of cellular quiescence by the transcriptional repressor HES1
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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
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Andrew P. Weng et al.
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Y Komeno et al.
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Prognostically useful gene-expression profiles in acute myeloid leukemia
PJM Valk et al.
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Biologic and clinical significance of the FLT3 transcript level in acute myeloid leukemia
K Ozeki et al.
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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
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T Ito et al.
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Notch1 functions as a tumor suppressor in mouse skin
M Nicolas et al.
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S Fröhling et al.
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Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision
H Han et al.
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Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells
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p300 acts as a transcriptional coactivator for mammalian Notch-1
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Association with the nuclear matrix and interaction with Groucho and RUNX proteins regulate the transcription repression activity of the basic helix loop helix factor Hes1
FW McLarrent et al.
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R Kageyama et al.
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F Hayakawa et al.
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