相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome
N. Villamor et al.
LEUKEMIA (2013)
Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma
Robert Kridel et al.
BLOOD (2012)
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Jinghui Zhang et al.
NATURE (2012)
NOTCH1 Signaling Promotes Human T-Cell Acute Lymphoblastic Leukemia Initiating Cell Regeneration in Supportive Niches
Wenxue Ma et al.
PLOS ONE (2012)
Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL
Jessica Tatarek et al.
BLOOD (2011)
Therapeutic potential of Notch inhibition in T-cell acute lymphoblastic leukemia: rationale, caveats and promises
Leonor M. Sarmento et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2011)
Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation
Giulia Fabbri et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells
M. Masiero et al.
LEUKEMIA (2011)
Expression of CD34 and CD7 on human T-cell acute lymphoblastic leukemia discriminates functionally heterogeneous cell populations
B. Gerby et al.
LEUKEMIA (2011)
A Molecularly Annotated Platform of Patient-Derived Xenografts (Xenopatients) Identifies HER2 as an Effective Therapeutic Target in Cetuximab-Resistant Colorectal Cancer
Andrea Bertotti et al.
CANCER DISCOVERY (2011)
Leukemia-initiating cells in human T-lymphoblastic leukemia exhibit glucocorticoid resistance
Priscilla P. L. Chiu et al.
BLOOD (2010)
The Notch/Hes1 Pathway Sustains NF-κB Activation through CYLD Repression in T Cell Leukemia
Lluis Espinosa et al.
CANCER CELL (2010)
Therapeutic antibody targeting of individual Notch receptors
Yan Wu et al.
NATURE (2010)
Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors
Miguel Aste-Amezaga et al.
PLOS ONE (2010)
Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
William Pao et al.
NATURE REVIEWS CANCER (2010)
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
Raphael Kopan et al.
CELL (2009)
Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia
Elaine Coustan-Smith et al.
LANCET ONCOLOGY (2009)
NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia
P. J. Real et al.
LEUKEMIA (2009)
Notch signaling in leukemia
Jon C. Aster et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)
CD7 expression and galectin-1-induced apoptosis of immature thymocytes Are directly regulated by NF-κB upon T-cell activation
Han S. Koh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
F-18FDG-PET imaging in adult T-cell leukemia lymphoma
Naoto Watanabe et al.
CLINICAL NUCLEAR MEDICINE (2008)
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2
Orbicia Riccio et al.
EMBO REPORTS (2008)
Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines
Takeaki Dohda et al.
EXPERIMENTAL CELL RESEARCH (2007)
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
Jennifer O'Neil et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling
Huw D. Lewis et al.
CHEMISTRY & BIOLOGY (2007)
Characterization of a progenitor cell population in childhood T-cell acute lymphoblastic leukemia
Charlotte V. Cox et al.
BLOOD (2007)
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
Teresa Palomero et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc
Vishva Mitra Sharma et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
Andrew P. Weng et al.
GENES & DEVELOPMENT (2006)
CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors
T. Palomero et al.
LEUKEMIA (2006)
High incidence of Notch-1 mutations in adult patients with T-cell acute lymphoblastic leukemia
MR Mansour et al.
LEUKEMIA (2006)
Activating Notch1 mutations in mouse models of T-ALL
J O'Neil et al.
BLOOD (2006)
Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease
JH van Es et al.
TRENDS IN MOLECULAR MEDICINE (2005)
Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia
A Castor et al.
NATURE MEDICINE (2005)
Chronic treatment with the γ-secretase inhibitor LY-411,575 inhibits β-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation
GT Wong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Notch regulation of lymphocyte development and function
F Radtke et al.
NATURE IMMUNOLOGY (2004)
Characterization of acute lymphoblastic leukemia progenitor cells
CV Cox et al.
BLOOD (2004)
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng et al.
SCIENCE (2004)
Detection of leukemic cells in the CD34+CD38- bone marrow progenitor population in children with acute lymphoblastic leukemia
AA George et al.
BLOOD (2001)
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