相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
Jakob Loven et al.
CELL (2013)
The Novel Orally Active Proteasome Inhibitor K-7174 Exerts Anti-myeloma Activity in Vitro and in Vivo by Down-regulating the Expression of Class I Histone Deacetylases
Jiro Kikuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Notch signaling from the endosome requires a conserved dileucine motif
Li Zheng et al.
MOLECULAR BIOLOGY OF THE CELL (2013)
Glucocorticoid sensitivity of T-cell lymphoblastic leukemia/lymphoma is associated with glucocorticoid receptor-mediated inhibition of Notch1 expression
S. Cialfi et al.
LEUKEMIA (2013)
Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial
S. Jenkinson et al.
LEUKEMIA (2013)
Regulation of Neurite Growth by Inorganic Pyrophosphatase 1 via JNK Dephosphorylation
Yu Tezuka et al.
PLOS ONE (2013)
Proteasome inhibitors in multiple myeloma: 10 years later
Philippe Moreau et al.
BLOOD (2012)
Bortezomib suppresses the growth of leukemia cells with Notch1 overexpression in vivo and in vitro
Chongmei Huang et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2012)
Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8
Taeko Wada et al.
EMBO REPORTS (2012)
Elevated SP-1 Transcription Factor Expression and Activity Drives Basal and Hypoxia-induced Vascular Endothelial Growth Factor (VEGF) Expression in Non-Small Cell Lung Cancer
Karl Deacon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Clinical Impact of NOTCH1 and/or FBXW7 Mutations, FLASH Deletion, and TCR Status in Pediatric T-Cell Lymphoblastic Lymphoma
Celine Callens et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid Tumors
Ian Krop et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors
Anthony W. Tolcher et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species
Vincenzo Giambra et al.
NATURE MEDICINE (2012)
Hes1 expression and CYLD repression are essential events downstream of Notch1 in T-cell leukemia
Teresa D'Altri et al.
CELL CYCLE (2011)
Significant Biological Role of Sp1 Transactivation in Multiple Myeloma
Mariateresa Fulciniti et al.
CLINICAL CANCER RESEARCH (2011)
Oncogenic and tumor suppressor functions of Notch in cancer: it's NOTCH what you think
Camille Lobry et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Interplay of Posttranslational Modifications in Sp1 Mediates Sp1 Stability during Cell Cycle Progression
Yi-Ting Wang et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells
Grace I. Aldana-Masangkay et al.
LEUKEMIA & LYMPHOMA (2011)
Notch in T-ALL: new players in a complex disease
Ute Koch et al.
TRENDS IN IMMUNOLOGY (2011)
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia
Fumio Nakahara et al.
BLOOD (2010)
Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma
Jiro Kikuchi et al.
BLOOD (2010)
Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia
Daniel Antunes Moreno et al.
BRITISH JOURNAL OF HAEMATOLOGY (2010)
The Notch/Hes1 Pathway Sustains NF-κB Activation through CYLD Repression in T Cell Leukemia
Lluis Espinosa et al.
CANCER CELL (2010)
Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
Ting-Chao Chou
CANCER RESEARCH (2010)
Therapeutic antibody targeting of individual Notch receptors
Yan Wu et al.
NATURE (2010)
Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors
Miguel Aste-Amezaga et al.
PLOS ONE (2010)
Differential Control of Notch1 Gene Transcription by Klf4 and Sp3 Transcription Factors in Normal versus Cancer-Derived Keratinocytes
Chiara Lambertini et al.
PLOS ONE (2010)
Biologic sequelae of IκB kinase (IKK) inhibition in multiple myeloma: therapeutic implications
Teru Hideshima et al.
BLOOD (2009)
Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells
Teru Hideshima et al.
BLOOD (2009)
γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity
Raymond D. Meng et al.
CANCER RESEARCH (2009)
Dual antitumor mechanisms of Notch signaling inhibitor in a T-cell acute lymphoblastic leukemia xenograft model
Shigeo Masuda et al.
CANCER SCIENCE (2009)
gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
Pedro J. Real et al.
NATURE MEDICINE (2009)
gamma-secretase inhibitors enhance taxane-induced mitotic arrest and apoptosis in colon cancer cells
Takashi Akiyoshi et al.
GASTROENTEROLOGY (2008)
Modulation of Notch signaling by antibodies specific for the extracellular negative regulatory region of NOTCH3
Kang Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Cooperation of Gata3, c-Myc and Notch in malignant transformation of double positive thymocytes
Jan Piet van Hamburg et al.
MOLECULAR IMMUNOLOGY (2008)
ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor
C. Osipo et al.
ONCOGENE (2008)
Targeting the NF-kappa B signaling pathway in Notch1-induced T-cell leukemia
Tomas Vilimas et al.
NATURE MEDICINE (2007)
Drug therapy - Treatment of acute lymphoblastic leukemia
CH Pui et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Notch1 augments NF-κB activity by facilitating its nuclear retention
HM Shin et al.
EMBO JOURNAL (2006)
Notch1 antiapoptotic activity is abrogated by caspase cleavage in dying T lymphocytes
LY Cohen et al.
CELL DEATH AND DIFFERENTIATION (2005)
Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats
C Sanchez-Irizarry et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng et al.
SCIENCE (2004)
MDM2 induces NF-κB/p65 expression transcriptionally through Sp1-binding sites:: a novel, p53-independent role of MDM2 in doxorubicin resistance in acute lymphoblastic leukemia
LB Gu et al.
BLOOD (2002)
Treatment of adult acute lymphoblastic leukemia (ALL): long-term follow-up of the GIMEMA ALL 0288 randomized study
L Annino et al.
BLOOD (2002)