相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia
Maddalena Paganin et al.
BLOOD REVIEWS (2011)
Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies
Jon C. Aster et al.
JOURNAL OF PATHOLOGY (2011)
Therapeutic antibody targeting of individual Notch receptors
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Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors
Miguel Aste-Amezaga et al.
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Metalloprotease ADAM10 Is Required for Notch1 Site 2 Cleavage
Geert van Tetering et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Selective Use of ADAM10 and ADAM17 in Activation of Notch1 Signaling
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MOLECULAR AND CELLULAR BIOLOGY (2009)
gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
Pedro J. Real et al.
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The role of NOTCH1 signaling in T-ALL
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Hematology-American Society of Hematology Education Program (2009)
Notch signaling in leukemia
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ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)
NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL
Maria Luisa Sulis et al.
BLOOD (2008)
Oncogenic NOTCH1 control of MYC and PI3K: Challenges and opportunities for anti-NOTCH1 therapy in T-cell acute lymphoblastic leukemias and lymphomas
Teresa Palomero et al.
CLINICAL CANCER RESEARCH (2008)
ADAM10 is essential for proteolytic activation of Notch during thymocyte development
Lei Tian et al.
INTERNATIONAL IMMUNOLOGY (2008)
Acute lymphoblastic leukaemia
Ching-Hon Pui et al.
LANCET (2008)
The ADAMs: signalling scissors in the tumour microenvironment
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TheEGF receptor family: spearheading a merger of signaling and therapeutics
Erez M. Bublil et al.
CURRENT OPINION IN CELL BIOLOGY (2007)
Targeting TACE-dependent EGFR ligand shedding in breast cancer
Paraic A. Kenny et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer
Bin-Bing S. Zhou et al.
CANCER CELL (2006)
CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors
T. Palomero et al.
LEUKEMIA (2006)
Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes
Michael J. Malecki et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
J Moffat et al.
CELL (2006)
Notch signalling: a simple pathway becomes complex
Sarah J. Bray
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Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the notch ligand, Delta-1
JO Manilay et al.
JOURNAL OF IMMUNOLOGY (2005)
Adams: Key components in EGFR signalling and development
CP Blobel
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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng et al.
SCIENCE (2004)
The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for α-secretase activity in fibroblasts
D Hartmann et al.
HUMAN MOLECULAR GENETICS (2002)
A novel proteolytic cleavage involved in Notch signaling:: The role of the disintegrin-metalloprotease TACE
C Brou et al.
MOLECULAR CELL (2000)
A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1
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