相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。A Higher-Order Complex Containing AF4 and ENL Family Proteins with P-TEFb Facilitates Oncogenic and Physiologic MLL-Dependent Transcription
Akihiko Yokoyama et al.
CANCER CELL (2010)
Phase I and Pharmacologic Study of SNS-032, a Potent and Selective Cdk2, 7, and 9 Inhibitor, in Patients With Advanced Chronic Lymphocytic Leukemia and Multiple Myeloma
Wei-Gang Tong et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia
Chengqi Lin et al.
MOLECULAR CELL (2010)
B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406
Maite P. Quiroga et al.
BLOOD (2009)
Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia
Mitch A. Phelps et al.
BLOOD (2009)
Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia
Rong Chen et al.
BLOOD (2009)
SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples
Andrew Conroy et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2009)
Proteomics strategy for quantitative protein interaction profiling in cell extracts
Kirti Sharma et al.
NATURE METHODS (2009)
Kinase drug discovery approaches in chronic myeloproliferative disorders
C. Kumar et al.
ONCOGENE (2009)
Identification of a Kinase Profile that Predicts Chromosome Damage Induced by Small Molecule Kinase Inhibitors
Andrew J. Olaharski et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
Targeting cancer with small molecule kinase inhibitors
Jianming Zhang et al.
NATURE REVIEWS CANCER (2009)
Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease
Christian Philipp Pallasch et al.
BLOOD (2008)
Translation of the Philadelphia chromosome into therapy for CML
Brian J. Druker
BLOOD (2008)
The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVHgenes
Aditya Veldurthy et al.
BLOOD (2008)
Negative selection of chronic lymphocytic leukaemia cells using a bifunctional rosette-based antibody cocktail
Salim Essakali et al.
BMC BIOTECHNOLOGY (2008)
The multi-tasking P-TEFb complex
Vanessa Bres et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
Robust and sensitive iTRAQ quantification on an LTQ orbitrap mass spectrometer
Marcus Bantscheff et al.
MOLECULAR & CELLULAR PROTEOMICS (2008)
A quantitative analysis of kinase inhibitor selectivity
Mazen W. Karaman et al.
NATURE BIOTECHNOLOGY (2008)
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases
Beth Apsel et al.
NATURE CHEMICAL BIOLOGY (2008)
Quantitative phosphoproteomics by mass spectrometry: Past, present, and future
Aleksandra Nita-Lazar et al.
PROTEOMICS (2008)
Cyclin-dependent kinase 9: a key transcriptional regulator and potential drug target in oncology, virology and cardiology
Shudong Wang et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification
Dorothee Mueller et al.
BLOOD (2007)
The biological and clinical relationship between CD5+23+ monoclonal B-cell lymphocytosis and chronic lymphocytic leukaemia
Andy C. Rawstron et al.
BRITISH JOURNAL OF HAEMATOLOGY (2007)
MLL translocations, histone modifications and leukaemia stem-cell development
Andrei V. Krivtsov et al.
NATURE REVIEWS CANCER (2007)
Chemical proteomics identifies unanticipated targets of clinical kinase inhibitors
Eric C. Peters et al.
ACS CHEMICAL BIOLOGY (2007)
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
Marcus Bantscheff et al.
NATURE BIOTECHNOLOGY (2007)
The Btk tyrosine kinase is a major target of the Bcr-Abi inhibitor dasatinib
Oliver Hantschel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Large-scale mapping of human protein-protein interactions by mass spectrometry
Rob M. Ewing et al.
MOLECULAR SYSTEMS BIOLOGY (2007)
Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity
Laura A. Smit et al.
BLOOD (2007)
The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling
Emmanuelle Bitoun et al.
HUMAN MOLECULAR GENETICS (2007)
R406, an orally available spleen tyrosine kinase inhibitor blocks Fc receptor signaling and reduces immune complex-mediated inflammation
Sylvia Braselmann et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Can we rationally design promiscuous drugs?
AL Hopkins et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2006)
Establishment of a novel human B-CLL-like xenograft model in nude mouse
S Loisel et al.
LEUKEMIA RESEARCH (2005)
Transcription inhibition by flavopiridol: mechanism of chronic lymphocytic leukemia cell death
R Chen et al.
BLOOD (2005)
Features of selective kinase inhibitors
ZA Knight et al.
CHEMISTRY & BIOLOGY (2005)
N-(Cycloalkylamino)acyl-2-aminothiazole inhibitors of cyclin-dependent kinase -: 2.: N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide (BMS-387032), a highly efficacious and selective antitumor agent
RN Misra et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs
DT Jones et al.
BLOOD (2004)
Advancing therapy for chronic lymphocytic leukemia - The role of rituximab
P Hillmen
SEMINARS IN ONCOLOGY (2004)
Novel molecular diagnostic and therapeutic targets in chronic lymphocytic leukaemia
A Gaiger et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2004)
Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents
PL Ross et al.
MOLECULAR & CELLULAR PROTEOMICS (2004)
Advances in chemotherapy for chronic lymphocytic leukemia
CM Wendtner et al.
SEMINARS IN HEMATOLOGY (2004)
Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors
D Brehmer et al.
MOLECULAR & CELLULAR PROTEOMICS (2004)
ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile
A Wiestner et al.
BLOOD (2003)
分享论文
