期刊
LETTERS IN APPLIED MICROBIOLOGY
卷 48, 期 1, 页码 90-96出版社
WILEY
DOI: 10.1111/j.1472-765X.2008.02494.x
关键词
antifungal; Brazilian green propolis; Brazilian red propolis; dermatophyte; Trichophyton sp
资金
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
- Universidade Federal de Pernambuco (UFPE)
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
- Rede de Colecoes de Culturas de Microrganismos do Norte e Nordeste do Brasil (RENNEBRA)
The in vitro antifungal activity of Brazilian green and red propolis was tested against different species of Trichophyton. The antifungal activity of the Brazilian aqueous and alcoholic extracts of the green propolis and the alcoholic extract of red propolis was observed against Trichophyton rubrum, Trichophyton tonsurans and Trichophyton mentagrohytes samples, using as controls itraconazole and terbinafine. The minimal inhibitory concentration was determined following the microdilution method indicated by the 'Clinical and Laboratory Standards Institute'. The minimal fungicide concentration was determined by the absence of growth in liquid sabouraud culture medium. The data obtained showed that the green propolis alcoholic extract's antifungal activity was from 64 to 1024 mu g ml(-1), whereas the red propolis alcoholic extract was from 8 to 1024 mu g ml(-1). The antifungal activity of the red propolis alcoholic extract was more efficient than the green propolis alcoholic extract for all three species studied. The T. rubrum samples were shown to be more sensitive to the antifungal activity of the alcoholic extracts of the propolis. The antifungal potential of the alcoholic extracts of green and red propolis demonstrated suggest an applicable potential as an alternative treatment for dermatophytosis caused by these species.
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