期刊
LASERS IN MEDICAL SCIENCE
卷 24, 期 2, 页码 129-136出版社
SPRINGER LONDON LTD
DOI: 10.1007/s10103-007-0536-9
关键词
Laser acupuncture; Pain; Osteoarthritis
资金
- NSFC [30572306]
- 973 Program of China [2005CB523306]
- Shanghai Science and Technology Developing Foundation [07DZ19722-2]
Our objective was to assess the efficacy and safety of combined 10.6 mu m and 650 nm laser irradiation on patients with knee osteoarthritis (OA). Forty patients with OA were randomly allocated to an active laser group or to a placebo laser group (20 per group). They either received active or sham laser treatment at acupoint Dubi (ST 35) in a total of 12 sessions. There was significant difference between the two groups in the Western Ontario and McMaster Universities (WOMAC) osteoarthritis index pain score change from baseline after 2 weeks of treatment (P = 0.047). The pain reduction of the active laser treatment group was 49%, whereas that of the placebo control group was only 13%. However, due to the high patient drop-out rate, the 4-week assessment could not be analyzed. Combined laser treatment seems beneficial to patients with knee OA. However, due to the small sample size and the high drop-out rate of patients in the placebo group, a large sample-size clinical trial is warranted to determine further the therapeutic efficacy of the device.
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