期刊
LARYNGOSCOPE
卷 119, 期 10, 页码 1941-1946出版社
WILEY
DOI: 10.1002/lary.20581
关键词
Methylene blue; encephalopathy; parathyroidectomy; monoamine oxidase A; monoamine oxidase inhibitor; serotonin syndrome; serotonin toxicity
Methylene blue has been used to help facilitate parathyroid surgery for over 30 years. Its use has been widely considered both safe and cost effective. Twenty-six cases of a toxic metabolic encephalopathy, however, have been reported with its use. As a result, some surgeons have stopped using this technique altogether. It is now known that methylene blue is a monoamine oxidase inhibitor. When combined with drugs that increase central serotonin neurotransmission, serotonin toxicity results. This is the cause of the encephalopathy described in the literature. A case report, review of the literature, and guidelines as to its proper use are presented so as to allow for safe parathyroid surgery.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据