Self-Assembly in the Mixtures of Surfactant and Dye Molecule Controlled via Temperature and β-Cyclodextrin Recognition

A new ternary system of tetradecyldimethylamine oxide (C(14)DMAO)/4-phenylazo benzoic acid (AzoH)/H2O was first investigated, and it was found that the self-assembly can be regulated via temperature and beta-cyclodextrin (beta-CD) recognition. In the temperature regulated self-assembly, the self-assembled phase structural transition between wormlike micelles and multilamellar vesicles (onions) were determined by cryogenic-transmission electron microscopy (cryo-TEM) images and H-2 nuclear magnetic resonance (H-2 NMR) spectra. The phase structural transition temperatures (PSTT) controlled by changing the amount of AzoH were measured by differential scanning calorimetry analysis. The self-assembled phase structural transition mechanism was discussed. It is argued that the self-assembled phase structural transition is the synergetic balance among the hydrophilic headgroup, steric structures of the hydrophobic chain, and membrane charge. beta-CD molecules were used as controlling hands to modulate the phase structural transition of self-assembly of the C(14)DMAO/AzoH/H2O system in solution via snatching C(14)DMAO molecules. The phase structural transitions from the threadlike micellar phase to the lamellar phase and from the lamellar phase to the vesicular phase can each be controlled because of the beta-CD molecular recognition. The phase structural transitions were confirmed by cryo-TEM observations and H-2 NMR measurements. The rheological properties were also investigated to display the importance in the phase structural transition. It was found that the dye molecule, AzoH, is harder to enclose by beta-CD than by C(14)DMAO because of the lower complex stability constant (i.e., KC14DMAO@beta-CD >> KAzoH@beta-CD. Therefore, the phase structural transition is mainly controlled by the inclusion of C(14)DMAO into the hydrophobic cavity of beta-CD molecules. The phase structural transition controlled via temperature and beta-CD may find potential applications such as in actuators, shape memories, drug delivery systems, and drag-reducing fluids, etc.