期刊
LANGMUIR
卷 28, 期 25, 页码 9878-9884出版社
AMER CHEMICAL SOC
DOI: 10.1021/la300867m
关键词
-
资金
- A4B CIRP Project from the Welsh Assembly Government [HE 09 COL 1022]
Antibodies were patterned onto flexible plastic films using the flexographic printing process. An ink formulation was developed using high molecular weight polyvinyl alcohol in carbonate bicarbonate buffer. In order to aid both antibody adhesion and the quality of definition in the printed features, a nitrocellulose coating was developed that was capable of being discretely patterned, thus increasing the signal-to-noise ratio of an antibody array. Printing antibody features such as dots, squares, text, and fine lines were reproduced effectively. Furthermore, this process could be easily adapted for printing of other biological materials, including, but not limited to, enzymes, DNA, proteins, aptamers, and cells.
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