期刊
LANGMUIR
卷 26, 期 23, 页码 18078-18082出版社
AMER CHEMICAL SOC
DOI: 10.1021/la102518t
关键词
-
资金
- FP7 nano DNA sequencing grant
- Swiss National Science Foundation (FNS) [200021-125319]
- Swiss National Science Foundation (SNF) [200021_125319] Funding Source: Swiss National Science Foundation (SNF)
We used AFM to investigate the interaction of polyelectrolytes such as ssDNA and dsDNA molecules with graphene as a substrate. Graphene is an appropriate substrate due to its planarity, relatively large surfaces that are detectable via an optical microscope, and straightforward identification of the number of layers. We observe that in the absence of the screening ions deposited ssDNA will bind only to the graphene and not to the SiO2 substrate, confirming that the binding energy is mainly due to the pi-pi stacking interaction. Furthermore, deposited ssDNA will map the graphene underlying structure. We also quantify the pi-pi stacking interaction by correlating the amount of deposited DNA with the graphene layer thickness. Our findings agree with reported electrostatic force microscopy (EFM) measurements. Finally, we inspected the suitability of using a graphene as a substrate for DNA origami-based nanostructures.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据