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EJ Paredes-Gamero et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Sp1/3 and NF-1 mediate basal transcription of the human P2X1 gene in megakaryoblastic MEG-01 cells
Jiangqin Zhao et al.
BMC MOLECULAR BIOLOGY (2006)
Ecto-nucleotidases of the CD39/NTPDase family modulate platelet activation and thrombus fori-nation: Potential as therapeutic targets
B Atkinson et al.
BLOOD CELLS MOLECULES AND DISEASES (2006)
The platelet P2 receptors in arterial thrombosis
C Gachet et al.
BLOOD CELLS MOLECULES AND DISEASES (2006)
The platelet ATP and ADP receptors
C Oury et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Use of microchip-based hydrodynamic focusing to measure the deformation-induced release of ATP from erythrocytes
Michael J. Moehlenbrock et al.
ANALYST (2006)
PI3-kinase is essential for ADP-stimulated integrin αIIbβ3-mediated platelet calcium oscillation, implications for P2Y receptor pathways in integrin αIIbβ3-initiated signaling cross-talks
DS Sun et al.
JOURNAL OF BIOMEDICAL SCIENCE (2005)
Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism
AR Hardy et al.
PLATELETS (2005)
The platelet P2 receptors as molecular targets for old and new antiplatelet drugs
C Gachet
PHARMACOLOGY & THERAPEUTICS (2005)
Ecto-hydrolysis of adenine nucleotides in rat blood platelets are altered by ovariectomy
D Pochmann et al.
PLATELETS (2005)
The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range
S Horner et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2005)
Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4′,4=,4=′-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid octasodium salt]
B Hechler et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms
AR Hardy et al.
BLOOD (2005)
P2Y12 gene H2 haplotype is not associated with increased adenosine diphosphate-induced platelet aggregation after initiation of clopidogrel therapy with a high loading dose
N von Beckerath et al.
BLOOD COAGULATION & FIBRINOLYSIS (2005)
Differential regulation and relocalization of the platelet P2Y receptors after activation:: A way to avoid loss of hemostatic properties?
A Baurand et al.
MOLECULAR PHARMACOLOGY (2005)
Red blood cell membrane fluctuations and shape controlled by ATP-induced cytoskeletal defects
NS Gov et al.
BIOPHYSICAL JOURNAL (2005)
ADP acting on P2Y13 receptors is a negative feedback pathway for ATP release from human red blood cells
LW Wang et al.
CIRCULATION RESEARCH (2005)
Activation of a P2Y(4)-like purinoceptor triggers an increase in cytosolic [Ca2+] in the red blood cells of the lizard Ameiva ameiva (Squamata, Teiidae)
R Sartorello et al.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2005)
Heterotrimeric G protein Gi is involved in a signal transduction pathway for ATP release from erythrocytes
JJ Olearczyk et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
Sensitivity limits for voltage control of P2Y receptor-evoked Ca2+ mobilization in the rat megakaryocyte
J Martinez-Pinna et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets
AR Hardy et al.
BLOOD (2004)
Tetrodotoxin-sensitive Na+ channels and muscarinic and purinergic receptors identified in human erythroid progenitor cells and red blood cell ghosts
JF Hoffman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Deformation-induced release of ATP from erythrocytes in a poly(dimethylsiloxane)-based microchip with channels that mimic resistance vessels
AK Price et al.
ANALYTICAL CHEMISTRY (2004)
Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP- and thrombin-induced human platelet activation
S Nylander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
NO inhibits signal transduction pathway for ATP release from erythrocytes via its action on heterotrimeric G protein Gi
JJ Olearczyk et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2004)
The effect of ebselen on adenine nucleotide hydrolysis by platelets from adult rats
CR Fürstenau et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2004)
Antiaggregatory activity in human platelets of potent antagonists of the P2Y1 receptor
M Cattaneo et al.
BIOCHEMICAL PHARMACOLOGY (2004)
ATP augments von Willebrand factor-dependent shear-induced platelet aggregation through Ca2+-calmodulin and myosin light chain kinase activation
C Oury et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Acetylsalicylic acid inhibits ATP diphosphohydrolase activity by platelets from adult rats
A Buffon et al.
CLINICA CHIMICA ACTA (2004)
Adenine triphosphate nucleotides are antagonists at the P2Y12 receptor
G Kauffenstein et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2004)
The P2Y1 receptor plays an essential role in the platelet shape change induced by collagen when TxA2 formation is prevented
P Mangin et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2004)
Extracellular ATP increases cation fluxes in human erythrocytes by activation of the P2X7 receptor
R Sluyter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Emerging roles for P2X1 receptors in platelet activation
MP Mahaut-Smith et al.
PLATELETS (2004)
Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis
C Vial et al.
BLOOD (2003)
GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge:: possible role in neuroimmune function
DJ Moore et al.
MOLECULAR BRAIN RESEARCH (2003)
Mechanisms involved in adenosine triphosphate-induced platelet aggregation in whole blood
NP Stafford et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2003)
Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects
P Fontana et al.
CIRCULATION (2003)
A role of the fast ATP-gated P2X, cation channel in thrombosis of small arteries in vivo
B Hechler et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype
C Oury et al.
BLOOD (2003)
Quantification of ADP and ATP receptor expression in human platelets
L Wang et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2003)
Heterologous cell-cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase-1)
AJ Marcus et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2003)
Both the ADP receptors P2Y(1) and P2Y(12), play a role in controlling shape change in human platelets
IA Jagroop et al.
PLATELETS (2003)
The relative importance of the ADP receptors, P2Y(12) and P2Y(1), in thrombin-induced platelet activation
S Nylander et al.
THROMBOSIS RESEARCH (2003)
ADP receptors-targets for developing antithrombotic agents
SP Kunapuli et al.
CURRENT PHARMACEUTICAL DESIGN (2003)
Role of extracellular ATP metabolism in regulation of platelet reactivity
AV Birk et al.
JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2002)
Functional significance of adenosine 5′-diphosphate receptor (P2Y12) in platelet activation initiated by binding of von Willebrand factor to platelet GP Ibα induced by conditions of high shear rate
S Goto et al.
CIRCULATION (2002)
A study of P2X(1) receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors
C Vial et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIB)beta(3) and ADP receptors
JG Jin et al.
BLOOD (2002)
Blockade of adenosine diphosphate receptors P2Y12 and P2Y1 is required to inhibit platelet aggregation in whole blood under flow
NA Turner et al.
BLOOD (2001)
An elusive receptor is finally caught:: P2Y12, an important drug target in platelets
EA Barnard et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2001)
Extracellular ATP activates a P2 receptor in Necturus erythrocytes during hypotonic swelling
DB Light et al.
JOURNAL OF MEMBRANE BIOLOGY (2001)
Novel structurally altered P2X1 receptor is preferentially activated by adenosine diphosphate in platelets and megakaryocytic cells
NJ Greco et al.
BLOOD (2001)
ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999
FL Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Adenosine diphosphate strongly potentiates the ability of the chemokines MDC, TARC, and SDF-1 to stimulate platelet function
ARL Gear et al.
BLOOD (2001)
Nucleotide receptors: an emerging family of regulatory molecules in blood cells
F Di Virgilio et al.
BLOOD (2001)
Identification of the platelet ADP receptor targeted by antithrombotic drugs
G Hollopeter et al.
NATURE (2001)
Are P2Y1 purinoceptors expressed in turkey erythrocytes?
K Sak
NEUROSCIENCE LETTERS (2000)
ADP can induce aggregation of human platelets via both P2Y(1) and P-2T receptors
GE Jarvis et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
A(2A) adenosine receptors in human peripheral blood cells
S Gessi et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets
MP Mahaut-Smith et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
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