期刊
LANCET
卷 374, 期 9700, 页码 1557-1565出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/S0140-6736(09)61421-5
关键词
-
资金
- Leducq Foundation
- Canadian Institutes of Health Research
- Heart and Stroke foundation of Canada
- NIHR Oxford Biomedical Research Centre
- Danish Research Agency
- Danish Heart Foundation
Reduction of the burden of ischaemia-reperfusion injury is the aim of most treatments for cardiovascular and cerebrovascular disease. Although many strategies have proven benefit in the experimental arena, few have translated to clinical practice. Scientific and practical reasons might explain this finding, but the unpredictability of acute ischaemic syndromes is one of the biggest obstacles to timely application of novel treatments. Remote ischaemic preconditioning-which is a powerful innate mechanism of multiorgan protection that can be induced by transient occlusion of blood flow to a limb with a blood-pressure cuff-could be close to becoming a clinical technique. Several proof-of-principle and clinical trials have been reported, suggesting that the technique has remarkable promise. We examine the history, development, and present state of remote preconditioning in cardiovascular disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据