期刊
LAB ON A CHIP
卷 13, 期 13, 页码 2484-2499出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3lc50415h
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资金
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- Winnipeg Rh Institute Foundation
- University of Manitoba
- Manitoba Health Research Council (MHRC)
Microfluidic devices can better control cellular microenvironments compared to conventional cell migration assays. Over the past few years, microfluidics-based chemotaxis studies showed a rapid growth. New strategies were developed to explore cell migration in manipulated chemical gradients. In addition to expanding the use of microfluidic devices for a broader range of cell types, microfluidic devices were used to study cell migration and chemotaxis in complex environments. Furthermore, high-throughput microfluidic chemotaxis devices and integrated microfluidic chemotaxis systems were developed for medical and commercial applications. In this article, we review recent developments in microfluidics-based chemotaxis studies and discuss the new trends in this field observed over the past few years.
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