期刊
LAB ON A CHIP
卷 13, 期 19, 页码 3956-3964出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3lc50558h
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- NIH Common Fund, through the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI), Office of the Director, NIH [U01 NS073474]
- Food and Drug Administration (FDA)
- Defense Advanced Research Projects Agency (DARPA) [W911NF-12-2-0036]
Polydimethylsiloxane (PDMS) has numerous desirable properties for fabricating microfluidic devices, including optical transparency, flexibility, biocompatibility, and fabrication by casting; however, partitioning of small hydrophobic molecules into the bulk of PDMS hinders industrial acceptance of PDMS microfluidic devices for chemical processing and drug development applications. Here we describe an attractive alternative material that is similar to PDMS in terms of optical transparency, flexibility and castability, but that is also resistant to absorption of small hydrophobic molecules.
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