期刊
LAB ON A CHIP
卷 12, 期 9, 页码 1591-1593出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2lc00014h
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资金
- Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan
- Grants-in-Aid for Scientific Research [09J04193, 23687021, 24107522, 22227005] Funding Source: KAKEN
We fabricated fluorescent nanoparticles which monitor temperature changes without sensitivity to pH (4-10) and ionic strength (0-500 mM). The nanothermometers spontaneously enter living HeLa cells via endocytosis, enclosed in acidic organelles, i.e., endosome/lysosome, and then transported along microtubules in a temperature-dependent manner, working as walking nanothermometers.
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