期刊
LAB ON A CHIP
卷 11, 期 9, 页码 1587-1592出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1lc20065h
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资金
- NSFC [20825622, 20990220, 20906064, 21036002, 21076127]
- National Basic Research Program of China [2009CB623407]
- Ministry of Education of China [200806100038, 20090181120045]
- NSF [DMR-1006546]
- Harvard MRSEC [DMR-0820484]
A hierarchical and scalable microfluidic device constructed from a combination of three building blocks enables highly controlled generation of multicomponent multiple emulsions. The number, ratio and size of droplets, each with distinct contents being independently co-encapsulated in the same level, can be precisely controlled. The building blocks are a drop maker, a connector and a liquid extractor; combinations of these enable the scale-up of the device to create higher-order multicomponent multiple emulsions with exceptionally diverse structures. These multicomponent multiple emulsions offer a versatile and promising platform for precise encapsulation of incompatible actives or chemicals, for synergistic delivery and biochemical and chemical reactions, and for engineering multicompartment materials with controlled internal phases.
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