期刊
LAB ON A CHIP
卷 11, 期 7, 页码 1249-1255出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0lc00587h
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资金
- Technology Strategy Board
- EPSRC
- EPSRC [TS/G001405/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [TS/G001405/1] Funding Source: researchfish
Counting the different subpopulations of cells in a fingerprick of human blood is important for a number of clinical point-of-care (PoC) applications. It is a challenge to demonstrate the integration of sample preparation and detection techniques in a single platform. In this paper we demonstrate a generic microfluidic platform that combines sample processing and characterisation and enumeration in a single, integrated system. Results of microfluidic 3-part differential leukocyte (granulocyte, lymphocyte and monocyte) counts, together with erythrocyte and thrombocyte (platelet) counts, in human blood are shown and corroborated with results from hospital clinical laboratory analysis.
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