期刊
LAB ON A CHIP
卷 9, 期 11, 页码 1631-1637出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b822081f
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资金
- NIH [RR199652, EB005753]
- Singapore-MIT Alliance,
- d'Arbeloff Fund for Excellence in Education
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R21EB005753] Funding Source: NIH RePORTER
We demonstrate a simple process for the fabrication of rigid plastic master molds for soft lithography directly from (poly) dimethysiloxane devices. Plastics masters (PMs) provide a cost-effective alternative to silicon-based masters and can be easily replicated without the need for cleanroom facilities. We have successfully demonstrated the use of plastics micromolding to generate both single and dual-layer plastic structures, and have characterized the fidelity of the molding process. Using the PM fabrication technique, world-to-chip connections can be integrated directly into the master enabling devices with robust, well-aligned fluidic ports directly after molding. PMs provide an easy technique for the fabrication of microfluidic devices and a simple route for the scaling-up of fabrication of robust masters for soft lithography.
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