期刊
LAB ON A CHIP
卷 9, 期 3, 页码 473-475出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b814697g
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资金
- le Fonds quebecois de la recherche sur la nature et les technologies (FQRNT)
- National Research Council of Canada
This article presents a multichannel droplet-based surface plasmon resonance platform. The platform comprises a digital electrowetting-on-dielectric (EWOD) microfluidic device coupled to surface plasmon resonance imaging (SPRi). SPRi is now a well-established detection technique that enables in-situ monitoring of multiple reactions occurring at the surface of the chip without the use of labels. Currently, the limiting factor in the application of SPRi for high-throughput applications is the flow-cell technology which relies on sequential sample processing within the continuous fluid flow. An original solution compared to the continuous flow-cell technology is proposed to increase the capability of existing SPRi technology. A parallel SPRi detection of different samples on the surface is achieved using the array-based digital microfluidic device.
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