期刊
LAB ON A CHIP
卷 9, 期 18, 页码 2738-2741出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b903687c
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资金
- National Science Foundation [ECCS-0824183, ECCS-0801922]
- Penn State Center for Nanoscale Science (MRSEC)
- NSF-funded National Nanotechnology Infrastructure Network
- Directorate For Engineering
- Div Of Electrical, Commun & Cyber Sys [0824183] Funding Source: National Science Foundation
We present ultra-fast homogeneous mixing inside a microfluidic channel via single-bubble- based acoustic streaming. The device operates by trapping an air bubble within a horse-shoe'' structure located between two laminar flows inside a microchannel. Acoustic waves excite the trapped air bubble at its resonance frequency, resulting in acoustic streaming, which disrupts the laminar flows and triggers the two fluids to mix. Due to this technique's simple design, excellent mixing performance, and fast mixing speed (a few milliseconds), our single-bubble-based acoustic micromixer may prove useful for many biochemical studies and applications.
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