期刊
LAB ON A CHIP
卷 9, 期 7, 页码 870-876出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b818873d
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资金
- Washington State's Life Sciences Discovery Fund (LSDF)
- National Institutes of Health [EB005197]
- Keck Foundation
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB005197] Funding Source: NIH RePORTER
As microfluidic systems transition from research tools to disposable clinical-diagnostic devices, new substrate materials are needed to meet both the regulatory requirement as well as the economics of disposable devices. This paper introduces a UV-curable polyurethane-methacrylate ( PUMA) substrate that has been qualified for medical use and meets all of the challenges of manufacturing microfluidic devices. PUMA is optically transparent, biocompatible, and exhibits high electroosmotic mobility without surface modification. We report two production processes that are compatible with the existing methods of rapid prototyping and present characterizations of the resultant PUMA microfluidic devices.
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