期刊
LAB ON A CHIP
卷 8, 期 12, 页码 2146-2150出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b811135a
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资金
- NIH EHS [R01 ES016665]
- N/MEMS S & T Fundamentals MF3 Center (DARPA)
- NSF
- NIH
- NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES [R01ES016665] Funding Source: NIH RePORTER
This article describes FLASH (Fast Lithographic Activation of Sheets), a rapid method for laboratory prototyping of microfluidic devices in paper. Paper-based microfluidic devices are emerging as a new technology for applications in diagnostics for the developing world, where low cost and simplicity are essential. FLASH is based on photolithography, but requires only a UV lamp and a hotplate; no clean-room or special facilities are required (FLASH patterning can even be performed in sunlight if a UV lamp and hotplate are unavailable). The method provides channels in paper with dimensions as small as 200 mu m in width and 70 mu m in height; the height is defined by the thickness of the paper. Photomasks for patterning paper-based microfluidic devices can be printed using an ink-jet printer or photocopier, or drawn by hand using a waterproof black pen. FLASH provides a straightforward method for prototyping paper-based microfluidic devices in regions where the technological support for conventional photolithography is not available.
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