期刊
LAB ON A CHIP
卷 8, 期 10, 页码 1617-1620出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/b807374k
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- UK Interdisciplinary Research Centre in Bio-Nanotechnology [R45659/01]
- European Commission [NMP4-CT-2005-017114]
We describe the formation of artificial bilayer lipid membranes (BLMs) by the controlled, electrical manipulation of aqueous droplets immersed in a lipid-alkane solution. Droplet movement was generated using dielectrophoresis on planar microelectrodes covered in a thin insulator. Droplets, surrounded by lipid monolayers, were brought into contact and spontaneously formed a BLM. The method produced BLMs suitable for single-channel recording of membrane protein activity and the technique can be extended to create programmable BLM arrays and networks.
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