期刊
PSYCHIATRY RESEARCH
卷 225, 期 1-2, 页码 93-98出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.psychres.2014.10.021
关键词
Clinical high risk; Cognition; Cognitive remediation therapy; Functional outcome
类别
资金
- Brain and Behaviour Research Fund Young Investigator Grant [17369]
- Alberta Innovates - Health Solutions [201000291]
- NIMH [U01MH08984]
Individuals at clinical high risk (CHR) of psychosis evidence cognitive deficits. Given suggestions that deficits in cognition are related to poor functional outcome, cognition is a good treatment target. The aim of this study was to test the efficacy of cognitive remediation therapy (CRT) in improving cognition of CHR individuals. Participants were tested at baseline, immediately following CRT and 9 months post-baseline. The mixed effects modelling demonstrated no differences in cognition between the experimental group and the control group at any time point. For the experimental group, however, there was a trend towards improvement in speed of processing between baseline and 9-month follow-up (t(29)= -2.91, P=0.06) and at post-CRT compared to 9-month follow-up (t(29)= -2.99, P < 0.05). In the control group, significant improvements in working memory were observed between post-CRT and 9-month follow-up (t(29)= -3.06, P < 0.05). Despite significant improvements in social functioning in the intervention group between baseline and 9-month follow-up (t(28)= -3.26, P < 0.05), these improvements were not correlated with cognition. There were trends towards improvement and no trends of decline in the two groups. While CRT may be valuable for individuals at CHR, the type of intervention employed needs to be carefully considered. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据