期刊
PSYCHIATRY AND CLINICAL NEUROSCIENCES
卷 69, 期 8, 页码 477-482出版社
WILEY
DOI: 10.1111/pcn.12286
关键词
general population; item response theory; probable REM sleep behavior disorder; REM Sleep Behavior Disorder Screening Questionnaire; receiver-operator curve
资金
- Philips Respironics GK
- Takeda Pharmaceutical Co., Ltd
- GlaxoSmithKline K.K.
- Astellas Pharma Inc.
- Sanofi-Aventis K.K.
- Yoshitomiyakuhin Co.
- Otsuka Pharmaceutical Co., Ltd
- Eisai Co., Ltd
- Grants-in-Aid for Scientific Research [26460907, 25515009] Funding Source: KAKEN
AimsIn order to evaluate the validity of the REM Sleep Behavior Disorder (RBD) Screening Questionnaire (RBDSQ) as a screening tool for RBD in a general population setting, we conducted a validation study using residents of a rural community. MethodsWe sent questionnaires that included the RBDSQ to 2631 eligible adult residents in the town of Daisen, Japan. ResultsOf those residents, 1572 participants (59.7%) gave complete answers to the RBDSQ. Among them, 179 participants (11.4%) scored 5 points on the questionnaire; an additional 149 participants scoring 4 points were randomly selected for further telephone interview. Based on obtained results, nine participants (0.57%) were judged as having probable RBD. Receiver-operator curve analysis revealed that a total score of 6 points on the RBDSQ represented the best cut-off value for detecting probable RBD (sensitivity: 100%; specificity: 73.0%). Analysis based on the item response theory revealed that items 1, 4, 6-1, 7, and 8 had lower difficulty than the remaining items, suggesting that these items are more essential in the screening for probable RBD. ConclusionsThe present study revealed that a score of 6 points on the RBDSQ could be used as a cut-off value for the screening of probable RBD in the general population. Evaluation of the distribution of positive items might be helpful for identifying the intensity of a person's RBD symptoms.
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