期刊
KIDNEY INTERNATIONAL
卷 75, 期 12, 页码 1257-1263出版社
ELSEVIER SCIENCE INC
DOI: 10.1038/ki.2009.92
关键词
accuracy; diagnosis; diagnostic strategy; epidemiology; nephrology; sensitivity and specificity
For most physicians, use of diagnostic tests is part of daily routine. This paper focuses on their usefulness by explaining the different measures of accuracy, the interpretation of test results, and the implementation of a diagnostic strategy. Measures of accuracy include sensitivity and specificity. Although these measures are often considered fixed properties of a diagnostic test, in reality they are subject to multiple sources of variation such as the population case mix and the severity of the disease under study. Furthermore, when evaluating a new diagnostic test, it must be compared to a reference standard, although the latter is usually not perfect. In daily practice diagnostic tests are not used in isolation. Several issues will influence the interpretation of their results. First, clinicians have a prior assumption about the patient's chances of having the disease under investigation, based on the patient's characteristics, symptoms, and the disease prevalence in similar populations. Second, diagnostic tests are usually part of a diagnostic strategy. Therefore, it is not sufficient to determine the accuracy of a single test; one also needs to determine its additional value to the patient's diagnosis, treatment, or outcome as part of a diagnostic strategy. Kidney International (2009) 75, 1257-1263; doi:10.1038/ki.2009.92; published online 1 April 2009
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据