期刊
KIDNEY INTERNATIONAL
卷 74, 期 1, 页码 9-11出版社
ELSEVIER SCIENCE INC
DOI: 10.1038/ki.2008.127
关键词
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资金
- NHLBI NIH HHS [HL749976, HL59976, R01 HL074966, R01 HL059976-08, R01 HL074966-04, R01 HL059976] Funding Source: Medline
Vascular access failure is a major clinical problem for patients on hemodialysis, but therapeutic approaches aimed at improving arteriovenous fistula (AVF) dysfunction remain elusive. Using a murine AVF model, Juncos et al. demonstrate for the first time that the stress protein heme oxygenase-1 (HO-1) is induced in AVFs and that HO-1 is a critical determinant of AVF survival.
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