相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR
Jordan Gallinetti et al.
BIOCHEMICAL JOURNAL (2013)
Fibroblasts from long-lived mutant mice exhibit increased autophagy and lower TOR activity after nutrient deprivation or oxidative stress
Min Wang et al.
AGING CELL (2012)
Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis
Rajasekhar N. V. S. Suragani et al.
BLOOD (2012)
Surgical Stress Resistance Induced by Single Amino Acid Deprivation Requires Gcn2 in Mice
W. Peng et al.
Science Translational Medicine (2012)
Heightened Induction of Proapoptotic Signals in Response to Endoplasmic Reticulum Stress in Primary Fibroblasts from a Mouse Model of Longevity
Amir A. Sadighi Akha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
Richard A. Miller et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2011)
Single-gene mutations and healthy ageing in mammals
Andrzej Bartke
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)
Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice
Jacob A. Panici et al.
FASEB JOURNAL (2010)
Both Transcriptional Regulation and Translational Control of ATF4 Are Central to the Integrated Stress Response
Souvik Dey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Longevity and Age-Related Pathology of Mice Deficient in Pregnancy-Associated Plasma Protein-A
Cheryl A. Conover et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2010)
The Aging Stress Response
Marcia C. Haigis et al.
MOLECULAR CELL (2010)
Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes
Liou Y. Sun et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
David E. Harrison et al.
NATURE (2009)
ATF4-dependent transcription mediates signaling of amino acid limitation
Michael S. Kilberg et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Yeast life span extension by depletion of 60S ribosomal subunits is mediated by Gcn4
Kristan K. Steffen et al.
CELL (2008)
Fibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stress
Adam B. Salmon et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2008)
Loss of pregnancy-associated plasma protein A extends lifespan in mice
Cheryl A. Conover et al.
AGING CELL (2007)
The double-strand RNA-dependent protein kinase PKR plays a significant role in a sustained ER stress-induced apoptosis
Eun-Soo Lee et al.
FEBS LETTERS (2007)
Common aging pathways in worms, flies, mice and humans
Stuart K. Kim
JOURNAL OF EXPERIMENTAL BIOLOGY (2007)
Reduced eIF2α phosphorylation and increased proapoptotic proteins in aging
Syed G. Hussain et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Pregnancy-associated plasma protein-A (PAPP-A): A local regulator of IGF bioavailability through cleavage of IGFBPs
Henning B. Boldt et al.
GROWTH HORMONE & IGF RESEARCH (2007)
Genome-wide identification of conserved longevity genes in yeast and worms
Erica D. Smith et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2007)
Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrest
SP Maynard et al.
AGING CELL (2006)
PERK and GCN2 contribute to eIF2α phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway
RB Hamanaka et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress
AB Salmon et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Translational regulation of GCN4 and the general amino acid control of yeast
AG Hinnebusch
ANNUAL REVIEW OF MICROBIOLOGY (2005)
Hormone-treated snell dwarf mice regain fertility but remain long lived and disease resistant
M Vergara et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2004)
Multiplex stress resistance in cells from long-lived dwarf mice
S Murakami et al.
FASEB JOURNAL (2003)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
The endocrine regulation of aging by insulin-like signals
M Tatar et al.
SCIENCE (2003)
Evolutionary medicine: From dwarf model systems to healthy centenarians?
VD Longo et al.
SCIENCE (2003)
Genes that prolong life: Relationships of growth hormone and growth to aging and life span
A Bartke et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
K Flurkey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Evidence that ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters
BA Kinney et al.
HORMONES AND BEHAVIOR (2001)
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
DJ Clancy et al.
SCIENCE (2001)
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
M Tatar et al.
SCIENCE (2001)
Glucose limitation induces GCN4 translation by activation of gcn2 protein kinase
RJ Yang et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Perk is essential for translational regulation and cell survival during the unfolded protein response
HP Harding et al.
MOLECULAR CELL (2000)