期刊
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
卷 65, 期 8, 页码 809-814出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/gerona/glq079
关键词
Fructose intake; Dementia; Ageing; Vascular health
资金
- European Research Area-Age Future Leaders of Ageing (FLARE)
- Medical Research Council [G0701539] Funding Source: researchfish
- MRC [G0701539] Funding Source: UKRI
The transition in the world age demographic toward older age is associated with an increased risk of neurodegenerative diseases, such as Alzheimer's disease. Risk profiles for dementia may also be changing. Obesity and type 2 diabetes have increased in prevalence in the last half-century and have been associated with increased dementia risk. Specific changes in nutrition may also represent a direct risk. A diet transition in the United States has occurred in the intake of refined sugar, particularly high-fructose corn syrup (HFCS) from a yearly estimate of 8.1 kg/person at the beginning of the XIX century to a current estimate of 65 kg/person. This article considers the association between refined sugar intake, markers of cardiovascular disease risk, and the possible promotion of the development of dementia.
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