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Jun-Beom Park et al.
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T. E. Reeves et al.
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Solid-phase PEGylation of recombinant interferon α-2a for site-specific modification:: Process performance, characterization, and in vitro bioactivity
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FM Veronese et al.
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C Roodveldt et al.
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Effect of pegylation on pharmaceuticals
JM Harris et al.
NATURE REVIEWS DRUG DISCOVERY (2003)
Effective drug delivery by PEGylated drug conjugates
RB Greenwald et al.
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Coordination number of zinc ions in the phosphotriesterase active site by molecular dynamics and quantum mechanics
J Koca et al.
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J Koca et al.
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S Gopal et al.
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Bioencapsulation within synthetic polymers (Part 1): sol-gel encapsulated biologicals
I Gill et al.
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