期刊
JOURNAL OF VIROLOGY
卷 89, 期 4, 页码 1951-1953出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.02966-14
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资金
- National Institutes of Health [R01 DK093668]
- American Heart Association [12GRNT12030041]
Viruses affect host physiology beyond causing acute disease, thereby giving rise to the concept that the virome is a component of the microbiome. However, the role of the enteric virome is understudied relative to the fast-paced research examining commensal bacteria in the intestine. In this article, I discuss our recent work on murine norovirus indicating that an animal virus in the intestine can provide many of the signals to the host that have been attributed to commensal bacteria. Our findings suggest that the surge in microbiome research should incorporate examination of the enteric virome.
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