期刊
JOURNAL OF VIROLOGY
卷 87, 期 12, 页码 7185-7190出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.00324-13
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资金
- National Institutes of Health [AI090196, AI079231, AI57158, AI070411, AI090055, AI072613, CA057973, EY017404]
- Division of Intramural Research, National Institute of Dental and Craniofacial Research
- Greenberg Medical Research Institute
- Starr Foundation
- Danish Council for Independent Research
- BBSRC [BBS/E/D/20241864] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BBS/E/D/20241864] Funding Source: researchfish
- Novo Nordisk Fonden [NNF12OC0002037] Funding Source: researchfish
The recent identification of nonprimate hepaciviruses in dogs and then in horses prompted us to look for pegiviruses (GB virus-like viruses) in these species. Although none were detected in canines, we found widespread natural infection of horses by a novel pegivirus. Unique genomic features and phylogenetic analyses confirmed that the tentatively named equine pegivirus (EPgV) represents a novel species within the Pegivirus genus. We also determined that EPgV causes persistent viremia whereas its clinical significance is undetermined.
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