期刊
JOURNAL OF VIROLOGY
卷 86, 期 10, 页码 5774-5781出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.00137-12
关键词
-
类别
资金
- National Institutes of Health (NIH) [HHSN2662000700010C, U54 AI057158-04, T32 AI07647]
- Erwin Schrodinger fellowship from Austrian Science Fund (FWF) [J 3232]
The influenza virus hemagglutinin molecule possesses a globular head domain that mediates receptor binding and a stalk domain at the membrane-proximal region. We generated functional influenza viruses expressing chimeric hemagglutinins encompassing a variety of globular head and stalk combinations, not only from different hemagglutinin subtypes but also from different hemagglutinin phylogenetic groups. These chimeric recombinant viruses possess growth properties similar to those of wildtype influenza viruses and can be used as reagents to measure domain-specific antibodies in virological and immunological assays.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据