期刊
JOURNAL OF VIROLOGY
卷 86, 期 2, 页码 1238-1243出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.06429-11
关键词
-
类别
资金
- National Institutes of Health [AI-045990]
Virion uncoating is an essential early event in reovirus infection. In natural enteric infections, rapid proteolytic uncoating of virions is mediated by pancreatic serine proteases. The proteases that promote reovirus disassembly and cell entry in the respiratory tract remain unknown. In this report, we show that endogenous respiratory and inflammatory proteases can promote reovirus infection in vitro and that preexisting inflammation augments in vivo infection in the murine respiratory tract.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据