期刊
JOURNAL OF VIROLOGY
卷 85, 期 17, 页码 9227-9234出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.00230-11
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资金
- Robert Koch Institute
- University of Bonn [O-156-0006]
- European Union DG Research [223498]
- EVA [228292]
The family Bunyaviridae is the most diversified family of RNA viruses. We describe a novel prototypic bunyavirus, tentatively named Gouleako virus, isolated from various mosquito species trapped in Cote d'Ivoire. The S segment comprised 1,087 nucleotides (nt), the M segment 3,188 nt, and the L segment 6,358 nt, constituting the shortest bunyavirus genome known so far. The virus had shorter genome termini than phleboviruses and showed no evidence of encoded NSs and NSm proteins. An uncharacterized 105-amino-acid (aa) putative open reading frame (ORF) was detected in the S segment. Genetic equidistance to other bunyaviruses (74 to 88% aa identity) and absence of serological cross-reactivity with phleboviruses suggested a proposed novel Bunyaviridae genus.
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