相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Non-native Soluble Oligomers of Cu/Zn Superoxide Dismutase (SOD1) Contain a Conformational Epitope Linked to Cytotoxicity in Amyotrophic Lateral Sclerosis (ALS)
Rachel L. Redler et al.
BIOCHEMISTRY (2014)
Identification of a Misfolded Region in Superoxide Dismutase 1 That Is Exposed in Amyotrophic Lateral Sclerosis
Melissa S. Rotunno et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
In-cell NMR reveals potential precursor of toxic species from SOD1 fALS mutants
Enrico Luchinat et al.
NATURE COMMUNICATIONS (2014)
An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis
Melissa S. Rotunno et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Corruption and Spread of Pathogenic Proteins in Neurodegenerative Diseases
Lary C. Walker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Effect of electrostatics on aggregation of prion protein Sup35 peptide
Alexander M. Portillo et al.
JOURNAL OF PHYSICS-CONDENSED MATTER (2012)
Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils
Jan Bieschke et al.
NATURE CHEMICAL BIOLOGY (2012)
Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS
Terrell E. Brotherton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Atomic View of a Toxic Amyloid Small Oligomer
Arthur Laganowsky et al.
SCIENCE (2012)
Dynamics of Nucleosomes Assessed with Time-Lapse High-Speed Atomic Force Microscopy
Atsushi Miyagi et al.
BIOCHEMISTRY (2011)
Gaia: automated quality assessment of protein structure models
Pradeep Kota et al.
BIOINFORMATICS (2011)
SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments
Peter I. Joyce et al.
MAMMALIAN GENOME (2011)
Automated minimization of steric clashes in protein structures
Srinivas Ramachandran et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2011)
ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2
Steve Pedrini et al.
HUMAN MOLECULAR GENETICS (2010)
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
Daryl A. Bosco et al.
NATURE NEUROSCIENCE (2010)
Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS
Adrian Israelson et al.
NEURON (2010)
Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis
Jared R. Auclair et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Modeling studies of the change in conformation required for cleavage of limited proteolytic sites
S.J. Hubbard et al.
PROTEIN SCIENCE (2010)
A Transient and Low-Populated Protein-Folding Intermediate at Atomic Resolution
Dmitry M. Korzhnev et al.
SCIENCE (2010)
Current Hypotheses for the Underlying Biology of Amyotrophic Lateral Sclerosis
Jeffrey D. Rothstein
ANNALS OF NEUROLOGY (2009)
Modifications of Superoxide Dismutase (SOD1) in Human Erythrocytes A POSSIBLE ROLE IN AMYOTROPHIC LATERAL SCLEROSIS
Kyle C. Wilcox et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
Hideki Nishitoh et al.
GENES & DEVELOPMENT (2008)
SOD1 and Amyotrophic Lateral Sclerosis: Mutations and Oligomerization
Lucia Banci et al.
PLOS ONE (2008)
Ab initio folding of proteins with all-atom discrete molecular dynamics
Feng Ding et al.
STRUCTURE (2008)
Modeling backbone flexibility improves protein stability estimation
Shuangye Yin et al.
STRUCTURE (2007)
Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models
Per Zetterstrom et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis
Arie Gruzman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: A possible general mechanism for familial ALS
Lucia Banci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS
Rishi Rakhit et al.
NATURE MEDICINE (2007)
Eris: an automated estimator of protein stability
Shuangye Yin et al.
NATURE METHODS (2007)
Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis
R Rakhit et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis
PA Jonsson et al.
BRAIN (2004)
The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis
SD Khare et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
M Arrasate et al.
NATURE (2004)
Unraveling the mechanisms involved in motor neuron degeneration in ALS
LI Bruijn et al.
ANNUAL REVIEW OF NEUROSCIENCE (2004)
Generalized-ensemble algorithms: enhanced sampling techniques for Monte Carlo and molecular dynamics simulations
Y Okamoto
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2004)
Mechanism for the α-helix to β-hairpin transition
F Ding et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2003)
Paradigm shifts in Alzheimer's disease and other neuro degenerative disorders: The emerging role of oligomeric assemblies
MD Kirkitadze et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
DW Cleveland et al.
NATURE REVIEWS NEUROSCIENCE (2001)
Role of the tertiary and quaternary structures in the stability of dimeric copper,zinc superoxide dismutases
ME Stroppolo et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)