期刊
JOURNAL OF UROLOGY
卷 188, 期 3, 页码 989-995出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.juro.2012.04.098
关键词
kidney; kidney calculi; tomography, x-ray computed; diagnosis; mathematics
资金
- National Institute of Health [DK83007, DK59933]
Purpose: We propose a method to improve the accuracy of volume estimation of kidney stones from computerized tomography images. Materials and Methods: The proposed method consisted of 2 steps. A threshold equal to the average of the computerized tomography number of the object and the background was first applied to determine full width at half maximum volume. Correction factors were then applied, which were precalculated based on a model of a sphere and a 3-dimensional Gaussian point spread function. The point spread function was measured in a computerized tomography scanner to represent the response of the scanner to a point-like object. Method accuracy was validated using 6 small cylindrical phantoms with 2 volumes of 21.87 and 99.9 mm(3), and 3 attenuations, respectively, and 76 kidney stones with a volume range of 6.3 to 317.4 mm(3). Volumes estimated by the proposed method were compared with full width at half maximum volumes. Results: The proposed method was significantly more accurate than full width at half maximum volume (p < 0.0001). The magnitude of improvement depended on stone volume with smaller stones benefiting more from the method. For kidney stones 10 to 20 mm(3) in volume the average improvement in accuracy was the greatest at 19.6%. Conclusions: The proposed method achieved significantly improved accuracy compared with threshold methods. This may lead to more accurate stone management.
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