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Heon Park et al.
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Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys
Masaya Baba et al.
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ML Nickerson et al.
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Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract
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