期刊
JOURNAL OF ULTRASOUND IN MEDICINE
卷 27, 期 4, 页码 517-535出版社
WILEY
DOI: 10.7863/jum.2008.27.4.517
关键词
arrhenius analysis; nonfetal tissue; output display standard; temperature increase threshold; thermal mechanism
资金
- NIBIB NIH HHS [R37 EB002641-10, R37EB002641, R37 EB002641, R37 EB002641-11] Funding Source: Medline
T his review evaluates the thermal mechanism for ultrasound-induced biological effects in postnatal subjects. The focus is the evaluation of damage versus temperature increase. A view of ultrasound-induced temperature increase is presented, based on thermodynamic Arrhenius analyses. The hyperthermia and other literature revealed data that allowed for an estimate of a temperature increase threshold of tissue damage for very short exposure times. This evaluation yielded an exposure time extension of the 1997 American Institute of Ultrasound in Medicine Conclusions Regarding Heat statement (American Institute of Ultrasound in Medicine, Laurel, MD) to 0.1 second for nonfetal tissue, where, at this exposure time, the temperature increase threshold of tissue damage was estimated to be about 18 degrees C. The output display standard was also evaluated for soft tissue and bone cases, and it was concluded that the current thermal indices could be improved to reduce the deviations and scatter of computed maximum temperature rises.
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