相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles
Jing L. Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
Christian Hansen et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Therapeutic applications of antibodies in non-infectious neurodegenerative diseases
Pavan K. Krishnamurthy et al.
NEW BIOTECHNOLOGY (2011)
Intermolecular transmission of superoxide dismutase 1 misfolding in living cells
Leslie I. Grad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells
Christian Muench et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Cellular prion protein released on exosomes from macrophages binds to Hsp70
Guihua Wang et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2010)
Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form
Aaron Kerman et al.
ACTA NEUROPATHOLOGICA (2010)
The Development of New Therapeutics for Alzheimer's Disease
M. D. Carter et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2010)
Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?
S. Zraika et al.
DIABETOLOGIA (2010)
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
Dorothee Dormann et al.
EMBO JOURNAL (2010)
Amyotrophic Lateral Sclerosis-associated Proteins TDP-43 and FUS/TLS Function in a Common Biochemical Complex to Co-regulate HDAC6 mRNA
Sang Hwa Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Prion-like disorders: blurring the divide between transmissibility and infectivity
Mimi Cushman et al.
JOURNAL OF CELL SCIENCE (2010)
The human G93A SOD1 phenotype closely resembles sporadic amyotrophic lateral sclerosis
Matthis Synofzik et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2010)
Generation and Therapeutic Efficacy of Highly Oligomer-Specific β-Amyloid Antibodies
Heinz Hillen et al.
JOURNAL OF NEUROSCIENCE (2010)
Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
Evangelia Emmanouilidou et al.
JOURNAL OF NEUROSCIENCE (2010)
Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice
Ya-Fei Xu et al.
JOURNAL OF NEUROSCIENCE (2010)
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
Ian R. A. Mackenzie et al.
LANCET NEUROLOGY (2010)
Amyloid-beta Oligomers: Possible Roles as Key Neurotoxins in Alzheimer's Disease
Alex L. Lublin et al.
MOUNT SINAI JOURNAL OF MEDICINE (2010)
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
Daryl A. Bosco et al.
NATURE NEUROSCIENCE (2010)
Prion-like transmission of protein aggregates in neurodegenerative diseases
Patrik Brundin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Cell-to-cell transmission of non-prion protein aggregates
Seung-Jae Lee et al.
NATURE REVIEWS NEUROLOGY (2010)
New leads for Parkinson's disease
Katie Kingwell
NATURE REVIEWS NEUROSCIENCE (2010)
Structural conversion of neurotoxic amyloid-β1-42 oligomers to fibrils
Mahiuddin Ahmed et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Wild-type human SOD1 overexpression does not accelerate motor neuron disease in mice expressing murine Sod1G86R
Jean-Nicolas Audet et al.
NEUROBIOLOGY OF DISEASE (2010)
Functional Alterations in Memory Networks in Early Alzheimer's Disease
Reisa A. Sperling et al.
NEUROMOLECULAR MEDICINE (2010)
Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS
Adrian Israelson et al.
NEURON (2010)
Novel Antibodies Reveal Inclusions Containing Non-Native SOD1 in Sporadic ALS Patients
Karin Forsberg et al.
PLOS ONE (2010)
Generating a Prion with Bacterially Expressed Recombinant Prion Protein
Fei Wang et al.
SCIENCE (2010)
Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis
Yvonne S. Eisele et al.
SCIENCE (2010)
Prions, protein homeostasis, and phenotypic diversity
Randal Halfmann et al.
TRENDS IN CELL BIOLOGY (2010)
The propagation of prion-like protein inclusions in neurodegenerative diseases
Michel Goedert et al.
TRENDS IN NEUROSCIENCES (2010)
Slaughtered aged cattle might be one dietary source exhibiting amyloid enhancing factor activity
Takuhiro Yoshida et al.
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS (2009)
Rethinking ALS: The FUS about TDP-43
Clotilde Lagier-Tourenne et al.
CELL (2009)
A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins
Simon Alberti et al.
CELL (2009)
Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse
Lijun Wang et al.
HUMAN MOLECULAR GENETICS (2009)
Misfolding of Proteins with a Polyglutamine Expansion Is Facilitated by Proteasomal Chaperones
Erwann Rousseau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Crowded Cell-like Environment Accelerates the Nucleation Step of Amyloidogenic Protein Misfolding
Zheng Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity
Brian S. Johnson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Propagation of Tau Misfolding from the Outside to the Inside of a Cell
Bess Frost et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Mimicking Aspects of Frontotemporal Lobar Degeneration and Lou Gehrig's Disease in Rats via TDP-43 Overexpression
Jason B. Tatom et al.
MOLECULAR THERAPY (2009)
CELL BIOLOGY Beyond the prion principle
Adriano Aguzzi
NATURE (2009)
Transmission and spreading of tauopathy in transgenic mouse brain
Florence Clavaguera et al.
NATURE CELL BIOLOGY (2009)
Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates
Pei-Hsien Ren et al.
NATURE CELL BIOLOGY (2009)
Wild-type Cu/Zn superoxide dismutase (SOD1) does not facilitate, but impedes the formation of protein aggregates of amyotrophic lateral sclerosis causing mutant SOD1
Heidrun Witan et al.
NEUROBIOLOGY OF DISEASE (2009)
ALS motor phenotype heterogeneity, focality, and spread Deconstructing motor neuron degeneration
John M. Ravits et al.
NEUROLOGY (2009)
Genetic variants in the promoter of TARDBP in sporadic amyotrophic lateral sclerosis
Natasha Luquin et al.
NEUROMUSCULAR DISORDERS (2009)
Neurodegenerative Diseases Target Large-Scale Human Brain Networks
William W. Seeley et al.
NEURON (2009)
The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids
Adriano Aguzzi et al.
NEURON (2009)
TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations
Satomi Maekawa et al.
NEUROPATHOLOGY (2009)
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
Paula Desplats et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Induction of cerebral β-amyloidosis: Intracerebral versus systemic Aβ inoculation
Yvonne S. Eisele et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
Caroline Vance et al.
SCIENCE (2009)
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
T. J. Kwiatkowski et al.
SCIENCE (2009)
50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis
Wendy J. Broom et al.
AMYOTROPHIC LATERAL SCLEROSIS (2008)
Superoxide dismutase: The cause of all amyotrophic lateral sclerosis?
Jorge Matias-Guiu et al.
ANNALS OF NEUROLOGY (2008)
Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity
H. Diana Rosas et al.
BRAIN (2008)
The endoplasmic reticulum-Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS
Makoto Urushitani et al.
FASEB JOURNAL (2008)
Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
Robyn A. Sharples et al.
FASEB JOURNAL (2008)
Proteasome activation as a novel antiaging strategy
Niki Chondrogianni et al.
IUBMB LIFE (2008)
Controlling the mass action of alpha-synuclein in Parkinson's disease
Changyoun Kim et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease
S. Rutger Leliveld et al.
JOURNAL OF NEUROSCIENCE (2008)
Amyloid β protein dimer-containing human CSF disrupts synaptic plasticity:: Prevention by systemic passive immunization
Igor Klyubin et al.
JOURNAL OF NEUROSCIENCE (2008)
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
Jia-Yi Li et al.
NATURE MEDICINE (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Research in motion: the enigma of Parkinson's disease pathology spread
Patrik Brundin et al.
NATURE REVIEWS NEUROSCIENCE (2008)
Fecal transmission of AA amyloidosis in the cheetah contributes to high incidence of disease
Beiru Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Selective assoction of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria
Christine Vande Velde et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Proteomic profiling of exosomes: Current perspectives
Richard J. Simpson et al.
PROTEOMICS (2008)
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
Jemeen Sreedharan et al.
SCIENCE (2008)
Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid
Laura J. Vella et al.
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY (2008)
Novel Mutations in TARDBP(TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis
Nicola J. Rutherford et al.
PLOS GENETICS (2008)
The DISC locus in psychiatric illness
J. E. Chubb et al.
MOLECULAR PSYCHIATRY (2008)
Normal prion protein trafficking in cultured human erythroblasts
Rebecca E. Griffiths et al.
BLOOD (2007)
Evidence for secretion of Cu,Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis
Catarina Gomes et al.
NEUROSCIENCE LETTERS (2007)
A general model of prion strains and their pathogenicity
John Collinge et al.
SCIENCE (2007)
Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis
Arie Gruzman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hot spots in prion protein for pathogenic conversion
Kazuo Kuwata et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Amyloidogenic potential of foie gras
Alan Solomon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Natural history and outcome in systemic AA amyloidosis
Helen J. Lachmann et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS
Rishi Rakhit et al.
NATURE MEDICINE (2007)
Focality of upper and lower motor neuron degeneration at the clinical onset of ALS
John Ravits et al.
NEUROLOGY (2007)
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
Makiko Nagai et al.
NATURE NEUROSCIENCE (2007)
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
Francesco Paolo Di Giorgio et al.
NATURE NEUROSCIENCE (2007)
Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43
Yvonne Davidson et al.
ACTA NEUROPATHOLOGICA (2007)
Toward molecular dissection of PrPC-PrPSc interactions
Laura Solforosi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Proteasome Activator Enhances Survival of Huntington's Disease Neuronal Model Cells
Hyemyung Seo et al.
PLOS ONE (2007)
Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis
Makoto Urushitani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Soluble protein oligomers in neurodegeneration:: lessons from the Alzheimer's amyloid β-peptide
Christian Haass et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Tetsuaki Arai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Exosomes: From biogenesis and secretion to biological function
Sascha Keller et al.
IMMUNOLOGY LETTERS (2006)
Identification and characterization of the nuclear localization/retention signal in the EWS proto-oncoprotein
Rouzanna P. Zakaryan et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: An independent component analysis
Kim A. Celone et al.
JOURNAL OF NEUROSCIENCE (2006)
Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host
Melanie Meyer-Luehmann et al.
SCIENCE (2006)
Alzheimer's disease β-amyloid peptides are released in association with exosomes
Lawrence Rajendran et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Tau protein hyperphosphorylation in sporadic ALS with cognitive impairment
MJ Strong et al.
NEUROLOGY (2006)
Cellular prion protein is released on exosomes from activated platelets
Catherine Robertson et al.
BLOOD (2006)
Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria
HX Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Aβ-induced meningoencephalitis is IFN-γ-dependent and is associated with T cell-dependent clearance of Aβ in a mouse model of Alzheimer's disease
A Monsonego et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
A specific amyloid-β protein assembly in the brain impairs memory
S Lesné et al.
NATURE (2006)
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
M Urushitani et al.
NATURE NEUROSCIENCE (2006)
3D structure of Alzheimer's amyloid-β(1-42) fibrils
T Lührs et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The most infectious prion protein particles
JR Silveira et al.
NATURE (2005)
Emerging prospects for the disease-modifying treatment of Alzheimer's disease
LC Walker et al.
BIOCHEMICAL PHARMACOLOGY (2005)
The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology
R Fujii et al.
CURRENT BIOLOGY (2005)
Glycine-rich proteins - A class of novel proteins
A Mousavi et al.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2005)
Natural oligomers of the amyloid-protein specifically disrupt cognitive function
JP Cleary et al.
NATURE NEUROSCIENCE (2005)
Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis
R Rakhit et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Prion diseases - Close to effective therapy?
NR Cashman et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
Cells release prions in association with exosomes
B Fevrier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A prion protein epitope selective for the pathologically misfolded conformation
E Paramithiotis et al.
NATURE MEDICINE (2003)
Sixteen novel mutations in the Cu/Zn superoxide dismutase gene in amyotrophic lateral sclerosis: a decade of discoveries, defects and disputes
PM Andersen et al.
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS (2003)
Antibodies against β-amyloid slow cognitive decline in Alzheimer's disease
C Hock et al.
NEURON (2003)
Staging of brain pathology related to sporadic Parkinson's disease
H Braak et al.
NEUROBIOLOGY OF AGING (2003)
Amyloid-β oligomers:: their production, toxicity and therapeutic inhibition
DM Walsh et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2002)
Ill-fated amyloid-β vaccine
MA Smith et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Stabilization of mutant Cu/Zn superoxide dismutase (SOD1) protein by coexpressed wild SOD1 protein accelerates the disease progression in familial amyotrophic lateral sclerosis mice
K Fukada et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
DW Cleveland et al.
NATURE REVIEWS NEUROSCIENCE (2001)
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
M Enari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Prion diseases of humans and animals: Their causes and molecular basis
J Collinge
ANNUAL REVIEW OF NEUROSCIENCE (2001)
Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1
D Jaarsma et al.
NEUROBIOLOGY OF DISEASE (2000)
Role of the proteasome in Alzheimer's disease
F Checler et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2000)
Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1
MS Ahmed et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2000)
Disruption of two novel genes by a translocation co-segregating with schizophrenia
JK Millar et al.
HUMAN MOLECULAR GENETICS (2000)
Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure
M von Bergen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Genetic factors in the early diagnosis of ALS
PM Andersen
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS (2000)