期刊
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
卷 6, 期 10, 页码 757-768出版社
WILEY
DOI: 10.1002/term.487
关键词
tissue engineering; scaffold; rhinoplasty; nasal reconstructive surgery; biomaterials; nanotechnology; stem cells
类别
资金
- Medical Research Council [G1001539] Funding Source: researchfish
- MRC [G1001539] Funding Source: UKRI
- Medical Research Council [G1001539] Funding Source: Medline
Cartilage tissue engineering is a rapidly progressing area of regenerative medicine with advances in cell biology and scaffold engineering constantly being investigated. Many groups are now capable of making neocartilage constructs with some level of morphological, biochemical, and histological likeness to native human cartilage tissues. The application of this useful technology in articular cartilage repair is well described in the literature; however, few studies have evaluated its application in head and neck reconstruction. Although there are many studies on auricular cartilage tissue engineering, there are few studies regarding cartilage tissue engineering for complex nasal reconstruction. This study therefore highlighted the challenges involved with nasal reconstruction, with special focus on nasal cartilage tissue, and examined how advancements made in cartilage tissue engineering research could be applied to improve the clinical outcomes of total nasal reconstructive surgery. Copyright (c) 2011 John Wiley & Sons, Ltd.
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