期刊
JOURNAL OF THORACIC ONCOLOGY
卷 4, 期 3, 页码 281-283出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/JTO.0b013e3181989565
关键词
Circulating tumor cells; Non-small cell lung cancer; EGFR mutation; CTC-chip
资金
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [P41EB002503, U01EB012493, R01EB008047] Funding Source: NIH RePORTER
- NIBIB NIH HHS [U01 EB012493, R01 EB008047, P41 EB002503] Funding Source: Medline
Circulating tumor cells (CTCs) are rare cells that originate from a malignancy and circulate freely in the peripheral blood. The ability to capture and study CTCs is an emerging field with implications for early detection, diagnosis, determining prognosis and monitoring of cancer, as well as for understanding the fundamental biology of the process of metastasis, Here, we review the development and initial clinical studies with a novel microfluidic platform for isolating these cells, the CTC-chip, and discuss its potential uses in the study of lung cancer.
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