期刊
JOURNAL OF THERMAL BIOLOGY
卷 38, 期 1, 页码 32-40出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jtherbio.2012.10.003
关键词
Bioheat transfer equation; Temperature estimation; Finite volume method; Inverse analysis; Parameter estimation; Cancer
This article deals with the numerical analysis to ascertain the presence of a tumor and to estimate its size and location in a tissue. Heat transfer in the tissue is modeled using the Pennes bioheat transfer equation, and is solved using the finite volume method. Consideration is given to 1-D brain and breast tissues. Temperature distributions in the tissues are specific to the tumor grades, its locations and sizes, and these are different than that of a normal tissue. With temperature distribution known a priori, estimations of the position and the size of a tumor are done using the inverse analysis. The proposed approach gives a correct estimation of the presence of a tumor and its location and size. (C) 2012 Elsevier Ltd. All rights reserved.
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