期刊
JOURNAL OF THEORETICAL BIOLOGY
卷 308, 期 -, 页码 105-114出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jtbi.2012.05.034
关键词
Model; Dynamics; Mean-field analysis; Simulation
资金
- National Natural Science Foundation of China [61171153]
- Foundation for the Author of National Excellent Doctoral Dissertation of PR China
- Zhejiang Provincial Natural Science Foundation of China [LR12F01001]
- Scientific Research Foundation for the Returned Overseas Chinese Scholars
- University of Electronic Science and Technology of China
We systematically investigate the stochastic dynamics of a single Hodgkin-Huxley neuron driven by stochastic excitatory and inhibitory input spikes via unreliable synapses in this paper. Based on the mean-filed theory, a novel intrinsic neuronal noise regulation mechanism stemming from unreliable synapses is presented. Our simulation results show that, under certain conditions, the stochastic resonance phenomenon is able to be induced by the unreliable synaptic transmission, which can be well explained by the theoretical prediction. To a certain degree, the results presented here provide insights into the functional roles of unreliable synapses in neural information processing. (C) 2012 Elsevier Ltd. All rights reserved.
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