期刊
JOURNAL OF THEORETICAL BIOLOGY
卷 267, 期 4, 页码 614-625出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jtbi.2010.08.017
关键词
Signal transduction; Intracellular transport; Protein motors; Microtubules; Discontinuous Galerkin methods
资金
- Interdipartimental CNR
We consider models of Ran-driven nuclear transport of molecules such as proteins in living cells The mathematical model presented is the first to take into account for the active transport of molecules along the cytoplasmic microtubules All parameters entering the models are thoroughly discussed The model is tested by numerical simulations based on discontinuous Galerkin finite element methods The numerical experiments are compared to the behavior observed experimentally (C) 2010 Elsevier Ltd All rights reserved
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