期刊
JOURNAL OF THE ROYAL SOCIETY INTERFACE
卷 11, 期 92, 页码 -出版社
ROYAL SOC
DOI: 10.1098/rsif.2013.1150
关键词
nanoparticles; glioblastoma exosomes; nanofilaments; intercellular communication; nanotechnology
资金
- MEXT WPI Programme: International Center for Materials Nanoarchitectonics (MANA), Japan
- CNSI
Exosomes are sub-100 nm extracellular vesicles secreted by normal and cancer cells. We present a high-resolution structure of previously unidentified nanofilaments on glioblastoma-derived exosomes, using nanoscale peak force imaging. These stiff, adhesive, trypsin-and RNAse-resistant surface nanofilaments add a new dimension to the current structural knowledge of exosome-mediated intercellular communication.
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